Peptide Database

Peptide NameCrotamine

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC169H261N49O43S6

DescriptionStandard

        HCFPKEKICLPPSSDFGKMDCRWRWKCCKKGSG
    

Molecular Weight3859.57 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)4.80

Net Charge (pH 7.4) 4.46

Charge Density (pH 7.0) 0.1454

GRAVY Index-0.85

Hydrophobic Moment 0.45

Boman Index-0.22

Instability Index79.31

Aliphatic Index 23.64

Aromaticity 0.1212

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1480.92

LogP -13.19

H-bond Donors 57.0

H-bond Acceptors 55.0

Rotatable Bonds 126.0

Heavy Atoms 267.0

Ring Count 10.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0234834 VERIFIED: YES

Provenance & Taxonomy

OrganismCrotalus durissus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)