Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC544H882N150O163S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTINMNWNIKTWMFKDSGRGTVHISKVFVTAIFSTPLDNTGPTSISLSSCRTTSGDIDIKLNGKR
    

Molecular Weight12227.92 Da

Isoelectric Point (pI)9.74

Net Charge (pH 7.0)5.21

Net Charge (pH 7.4) 4.97

Charge Density (pH 7.0) 0.0457

GRAVY Index0.00

Hydrophobic Moment 0.54

Boman Index0.11

Instability Index23.13

Aliphatic Index 96.58

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5007.65

LogP -56.77

H-bond Donors 178.0

H-bond Acceptors 174.0

Rotatable Bonds 406.0

Heavy Atoms 860.0

Ring Count 17.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072662 VERIFIED: NO

Provenance & Taxonomy

OrganismOrigma solitaria [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria