Peptide Database

Peptide NameHolotricin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC408H652N120O109S9

DescriptionStandard

        MKFAIILAISAAMCIFRVSAFPLDEALEDEPLAEHVRHKRFTCDVLSAEFGTIKLNHAACATHCLFRLRGGGYCNARRVCICR
    

Molecular Weight9270.87 Da

Isoelectric Point (pI)8.57

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.26

Charge Density (pH 7.0) 0.0337

GRAVY Index0.33

Hydrophobic Moment 0.49

Boman Index0.08

Instability Index44.37

Aliphatic Index 94.22

Aromaticity 0.0843

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3646.11

LogP -31.41

H-bond Donors 137.0

H-bond Acceptors 125.0

Rotatable Bonds 305.0

Heavy Atoms 646.0

Ring Count 13.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069034 VERIFIED: NO

Provenance & Taxonomy

OrganismAsbolus verrucosus [Bacterium]

Tax ID1661398

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal