Peptide Database

Peptide NameSLAY-screened peptide P1501

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC105H162N28O26

DescriptionStandard

        EPFPFALSQPPLLHGQVKAR
    

Molecular Weight2232.58 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)0.92

Net Charge (pH 7.4) 0.70

Charge Density (pH 7.0) 0.0461

GRAVY Index-0.24

Hydrophobic Moment 0.23

Boman Index0.09

Instability Index66.52

Aliphatic Index 83.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 841.37

LogP -5.67

H-bond Donors 26.0

H-bond Acceptors 28.0

Rotatable Bonds 66.0

Heavy Atoms 159.0

Ring Count 7.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240791 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/