Peptide Database

Peptide NameScyliorhinin-2

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Tachykinin peptide

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC77H120N20O27S3

DescriptionStandard

        SPSNSKCPDGPDCFVGLM
    

Molecular Weight1854.09 Da

Isoelectric Point (pI)4.21

Net Charge (pH 7.0)-1.56

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0866

GRAVY Index-0.26

Hydrophobic Moment 0.36

Boman Index0.07

Instability Index42.16

Aliphatic Index 37.78

Aromaticity 0.0556

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 736.05

LogP -10.09

H-bond Donors 25.0

H-bond Acceptors 29.0

Rotatable Bonds 55.0

Heavy Atoms 127.0

Ring Count 4.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058433 VERIFIED: YES

Provenance & Taxonomy

OrganismScyliorhinus canicula [Animal]

FamilyScyliorhinin

Tax ID7830

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide7-13

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Vasoactive Vasodilator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0246648 VERIFIED: NO

Provenance & Taxonomy

OrganismScyliorhinus canicula [Animal]

FamilyTachykinin

Tax ID7830

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Tachykinin Neuropeptide Neuromodulator

RECORD: Rec_0309691 VERIFIED: NO

Provenance & Taxonomy

OrganismScyliorhinus canicula [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0379838 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/