‹ ›
MYP_088400
← PREVIOUS NEXT → BACK
Basic Information
FP3(FCoV Sgp (1338-1373))
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
36 amino acids
C185H292N46O61
Standard
Sequence
FNATYLNLTGEIDDLEFRSEKLHNTTVELAILIDNI
Physicochemical Analysis
4136.57 Da
4.19
-5.14
-5.41
-0.1428
-0.03
0.39
0.10
47.59
121.94
0.0833
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1753.26
-15.15
59.0
57.0
139.0
292.0
4.0
39.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0095553 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Fusion inhibition
feline coronavirus (FCoV) | Fcwf-4 cells
14.21 μM
IC50
Mammalian: 1.1 h; Yeast: 3 min; E. coli: 2 min
PaperPeptides corresponding to the predicted heptad repeat 2 domain of the feline coronavirus spike protein are potent inhibitors of viral infection. | Liu IJ, Tsai WT, Hsieh LE, Chueh LL. | PLoS One. 2013 Dec 3;8(12):e82081. | DOI:10.1371/journal.pone.0082081 | PMID:24312629 PMID24312629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24312629/
RECORD: Rec_0125676 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Fcwf-4 cells
>=200 μM
Cytotoxicity
PMID24312629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24312629/
RECORD: Rec_0241684 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Feline Coronavirus (FCoV)
PMID24312629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24312629/
RECORD: Rec_0270279 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PMID24312629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24312629/
RECORD: Rec_0284640 VERIFIED: YES
Provenance & Taxonomy
Feline coronavirus [Virus]
HR2-derived fusion inhibitor
33734
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Feline coronavirus
14.21 μM
IC50
PaperPeptides corresponding to the predicted heptad repeat 2 domain of the feline coronavirus spike protein are potent inhibitors of viral infection PMID24312629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24312629/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2