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MYP_088315
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Basic Information
Mastoparan-VT7
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C65H111N19O17
Standard
Sequence
INLKAIAALARNY
Physicochemical Analysis
1430.69 Da
9.99
1.76
1.55
0.1352
0.55
0.57
0.16
12.19
150.77
0.0769
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
606.85
-4.43
21.0
19.0
47.0
101.0
1.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0136265 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Klebsiella pneumoniae ATCC 700603
80 μM
MIC
PaperAntimicrobial peptides from the venom gland of the social wasp Vespa tropica.
RECORD: Rec_0137439 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa IS 350#
10 μM
MIC
PaperAntimicrobial peptides from the venom gland of the social wasp Vespa tropica.
RECORD: Rec_0137590 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
Hemolysis
PMID24012601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24012601/
RECORD: Rec_0145963 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0178402 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli IS 37#
80 μM
MIC
PaperAntimicrobial peptides from the venom gland of the social wasp Vespa tropica.
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