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MYP_088310
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Basic Information
Dermaseptin S4 (1-10)AMD[M4K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
10 amino acids
C59H102N14O12
Standard
Sequence
ALWKTLLKKV
Physicochemical Analysis
1199.53 Da
10.30
2.79
2.60
0.2793
0.41
0.53
0.11
15.70
156.00
0.1000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
439.30
0.07
16.0
15.0
41.0
85.0
2.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0112436 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (50% Hemolysis at >50 μM
50 μM
Hemolysis
PMID11847217;16436700 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11847217/
RECORD: Rec_0211661 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Staphylococcus aureus
50 μM
MIC
PMID11847217;16436700 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11847217/
RECORD: Rec_0230453 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Leishmania major
50 μM
LC50
PMID11847217;16436700 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11847217/
RECORD: Rec_0240057 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Cryptococcus neoformans B3501
30
MIC
PMID11847217;16436700 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11847217/
RECORD: Rec_0260686 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Escherichia coli
50
MIC
PMID11847217;16436700 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11847217/
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