Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1187 amino acids

Chemical FormulaC5855H9096N1650O1787S35

DescriptionStandard

        MDNWLALFDGQTRYFLDIFDSSVKPDVLRFYGREALSEPFSWDIEFTTLQANIPPEEVLMKYASFRMRSGKSVHGMVTRLEWLSTSKDQSHYRLTISSRLALLGYTRQCVVYQNQSVPEVVEQVLRKHGLEGPDFEFRLERTYPPREIITQWRETDLQFIQRILSEVGIYWRTEMDDVRGLDTYILADSQLNYQFDVQLPYSEPSGLFDSVAESVWDVRTWHNIATGTVTTRDYNYRTATMPMNAAVSVRNDVVTTGEHYRYAAPYREAGDDASPEPETESGAFWARLHHERELNRSARIHLFSNAAHLTPGQVLEPQGDVITALQEGVILTLVTFRGARDSRLHVSVWGQPYTERYCFRPAEIPRPVIAGTLPARIESREKNDTYAHLDEQGRYRVKQDFDREGTKPGYGYLWLRMAKPYAGETLGWHTPLIDGTEVAIAYSNGDIDLPYIACALHDSEHPDLVNRDNHTRNILRTPANSKLRMEDKRGEEHIKLATEYGKTQLNNGHLVNSKGQLRGKGTELRTDEWGVLRAGKGLFVAADVQAKAQGDALDMDAALKEIDRLNQQLQQLEMAAEKALALKGDVDSQIQMFEQRLKPLNEAVLFSAPEGMALTSGEDMQLAAGRNLALNAGEDFSAGVMGNATALTGEKLGLFARTGQLSLKSGEGPIDVQAQNASMRLFAEKKLTLSSASDISFAGKKRITLIGGGSYLKLEAGKVEYGTTASYVRKVKRTMAASASAKPPEAVSLPPPATMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVDNFGQMTIFAQPVEDDCCGYGHQHEHADDEVVQHAQSAKKRKPDAGGAQATAAPLALGAATGVMTQVWGEWSLTGVLGAARGIPYVGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKAITGAKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMVWNSEHNQYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIKPIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKTARDEPGVATGKGETLSGSEKWLEAASSGLGAPVPAQVADKLRGKSFRNFDHFREEFWLAVAECPELMSQFKRVNQMEIRDGNAPFSIVPEQVGGRKRFEIHHIERIIDGGAVYDFENMRVNTVRNHINLHSKKNR
    

Molecular Weight132315.12 Da

Isoelectric Point (pI)5.57

Net Charge (pH 7.0)-27.72

Net Charge (pH 7.4) -29.92

Charge Density (pH 7.0) -0.0234

GRAVY Index-0.50

Hydrophobic Moment 0.74

Boman Index-0.04

Instability Index34.95

Aliphatic Index 74.82

Aromaticity 0.0876

Extinction Coeff. Reduced 178080.00

Extinction Coeff. Oxidized 178580.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0181761 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyVgrG protein family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)