Peptide Database

Peptide NameAlpha-S2-casein [Cleaved into: Casocidin-1 (Casocidin-I)]

Function Ontology

Annotation / Protein functional class ▸ Storage protein

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Adverse immune reactivity ▸ Allergenicity ▸ Allergen

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length222 amino acids

Chemical FormulaC1166H1835N303O354S8

DescriptionStandard

        MKFFIFTCLLAVALAKNTMEHVSSSEESIISQETYKQEKNMAINPSKENLCSTFCKEVVRNANEEEYSIGSSSEESAEVATEEVKITVDDKHYQKALNEINQFYQKFPQYLQYLYQGPIVLNPWDQVKRNAVPITPTLNREQLSTSEENSKKTVDMESTEVFTKKTKLTEEEKNRLNFLKKISQRYQKFALPQYLKTVYQHQKAMKPWIQPKTKVIPYVRYL
    

Molecular Weight26018.38 Da

Isoelectric Point (pI)8.55

Net Charge (pH 7.0)2.77

Net Charge (pH 7.4) 2.26

Charge Density (pH 7.0) 0.0125

GRAVY Index-0.70

Hydrophobic Moment 0.68

Boman Index-0.11

Instability Index44.68

Aliphatic Index 73.74

Aromaticity 0.1036

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0179351 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyAlpha-casein

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0267113 VERIFIED: NO