Peptide Database

Peptide NameAlpha-defensin 10 (Defensin-related cryptdin-10)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC439H719N129O146S9

DescriptionStandard

        MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRKRGCKGRERMNGTCRKGHLLYTMCCR
    

Molecular Weight10428.77 Da

Isoelectric Point (pI)5.11

Net Charge (pH 7.0)-3.45

Net Charge (pH 7.4) -3.83

Charge Density (pH 7.0) -0.0371

GRAVY Index-0.53

Hydrophobic Moment 0.62

Boman Index-0.14

Instability Index36.23

Aliphatic Index 73.33

Aromaticity 0.0430

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4493.67

LogP -51.61

H-bond Donors 161.0

H-bond Acceptors 153.0

Rotatable Bonds 358.0

Heavy Atoms 723.0

Ring Count 8.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0316655 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found