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MYP_088220
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Basic Information
Esculentin-2CHa
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
37 amino acids
C173H289N47O47S2
Standard
Sequence
GFSSIFRGVAKFASKGLGKDLAKLGVDLVACKISKQC
Physicochemical Analysis
3843.56 Da
9.79
4.74
4.49
0.1280
0.37
0.75
0.12
15.63
97.57
0.0811
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1527.55
-14.86
56.0
54.0
135.0
269.0
3.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0365368 VERIFIED: YES
Provenance & Taxonomy
Lithobates chiricahuensis [Animal]
Esculentin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Stenotrophomonas maltophilia
PMID21262304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21262304/
RECORD: Rec_0370758 VERIFIED: YES
Provenance & Taxonomy
Lithobates chiricahuensis [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Escherichia coli
5 μM
MIC
RECORD: Rec_0384869 VERIFIED: YES
Provenance & Taxonomy
Lithobates chiricahuensis [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
31-37
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
fungi Candida albicans ATCC 90028
10 μM
MIC
PaperCharacterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona
RECORD: Rec_0392740 VERIFIED: YES
Provenance & Taxonomy
Lithobates chiricahuensis [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
31-37
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Klebsiella pneumoniae ATCC 700603
5 μM
MIC
PaperCharacterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona
RECORD: Rec_0396312 VERIFIED: YES
Provenance & Taxonomy
Lithobates chiricahuensis [Animal]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
31-37
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
5 μM
MIC
PMID21262304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21262304/
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