Peptide Database

Peptide NameLL-37 (17-29)[F1W,Q6R,K9W,D10R,F11W]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC92H146N32O14

DescriptionStandard

        WKRIVRRIWRWLR
    

Molecular Weight1924.35 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.4430

GRAVY Index-0.93

Hydrophobic Moment 1.23

Boman Index-0.52

Instability Index140.21

Aliphatic Index 112.31

Aromaticity 0.2308

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 795.41

LogP -1.37

H-bond Donors 33.0

H-bond Acceptors 20.0

Rotatable Bonds 62.0

Heavy Atoms 138.0

Ring Count 6.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403420 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus epidermidis(KCTC 1917)

Activity8 μM

MethodMIC

FIRST PREV 1 2 3 4

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