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MYP_088132
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Basic Information
Insulin-like growth factor II
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological regulation
Standard
68 amino acids
C324H510N94O103S6
Standard
Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSSRGIVEECCFRSCDLALLETYCATPAKSE
Physicochemical Analysis
7562.47 Da
6.46
-0.24
-0.54
-0.0036
-0.23
0.91
-0.09
80.25
64.56
0.1029
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3190.11
-37.43
122.0
109.0
245.0
527.0
10.0
68.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0166953 VERIFIED: NO
Provenance & Taxonomy
Neovison vison [Animal]
Insulin
452646
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
Evidence URLhttps://www.uniprot.org/uniprotkb/IGF2_NEOVI/entry
RECORD: Rec_0203522 VERIFIED: YES
Provenance & Taxonomy
Neogale vison [Animal]
Insulin-like growth factor
452646
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
9-48; 21-61; 47-52
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation ACE inhibitory
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Insulin-like growth factor II (Neovison vison): PMID 7686523 PMID7686523 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7686523/
RECORD: Rec_0333596 VERIFIED: YES
Provenance & Taxonomy
Neogale vison [Animal]
Insulin-like growth factor
452646
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
9-48; 21-61; 47-52
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation ACE inhibitory
glucose metabolism in adipose tissue
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Insulin-like growth factor II (Neovison vison): PMID 7686523 PMID7686523 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7686523/
RECORD: Rec_0378882 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/