Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length474 amino acids

Chemical FormulaC2359H3721N605O663S16

DescriptionStandard

        MAWRLAVAFMVAVYVENAGAINPGFVVRVTNKGLDYARQIGITVLQKELSTIKLPDFSGTFHIKHLGKGYYSFHDLVIRNFQLPSSQVEPVPNVGLKLSISDGFVQLDGQWHVKKSFIKDHGSFDLKVEGLSVSVGLALGSDSSGRPTVSAASCSSHISNVRVHISGKLSWLLDLFHKKIDAEFRKVMEDKICPVVSESINSKLQPILQTLPVTAKIDHIAGVDYSLLGPPIATAESVDVNLKGECFDLAHRSTVPFPPPAIAFPVDHNLMVYCGVSDYFFNTASFVYQAAGALIFNVTDDMIPKDFQMRLNTSTFGSLIPQVQKMYPNMLMKLMMSTPSAPVLKITPGNLTIAPALDFQAFAILPNSSLAPLFLLGVTTDVSAKIAVNSTRIVGSLALSRLQMTLKHSDVGPFSVALLDVAVNFYVSNILLPQINGKLERGFPLPLLDHVQLTDLILKPQQDFLQLGANINYG
    

Molecular Weight51678.47 Da

Isoelectric Point (pI)7.73

Net Charge (pH 7.0)1.62

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0034

GRAVY Index0.25

Hydrophobic Moment 0.70

Boman Index0.19

Instability Index36.87

Aliphatic Index 106.29

Aromaticity 0.0865

Extinction Coeff. Reduced 32890.00

Extinction Coeff. Oxidized 33140.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0245895 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocaecilia unicolor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria