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MYP_088059
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Basic Information
Amolopin-2a (Frogs, amphibians, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Adverse immune reactivity ▸ Histamine-release modulation
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
16 amino acids
C79H135N17O19
Standard
Sequence
FLPIVGKLLSGLSGLL
Physicochemical Analysis
1627.02 Da
8.75
0.76
0.55
0.0474
1.62
0.44
0.61
0.19
188.75
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
557.51
-1.59
19.0
20.0
53.0
115.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0277542 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Cytotoxic
PMID17000029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17000029/
RECORD: Rec_0314073 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Amolopin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Mast cell degranulation Histamine releasing
PaperYi Lu et al. / Peptides 27 (2006) 3085-3091. Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis Evidence URLhttps://www.uniprot.org/uniprotkb/A0SN46/entry
RECORD: Rec_0347422 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Amolopin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
1.84 μM
MIC
PaperYi Lu et al. / Peptides 27 (2006) 3085-3091. Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis Evidence URLhttps://www.uniprot.org/uniprotkb/A0SN46/entry
RECORD: Rec_0364126 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
3 μg/mL
MIC
PMID17000029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17000029/
RECORD: Rec_0389586 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Escherichia coli, B. dysenteriae
1.5-3.0 μg/mL
MIC
PaperTwo families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis
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