Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length102 amino acids

Chemical FormulaC495H802N140O151S12

DescriptionStandard

        MSVMKPCLMTIAILMILAQKTPGGLFRSHSGKSREPWNPCELYQGMCRNTCRKYEIQYLTCPNDQKCCLKLSVKITSSKNVKENYDSNSNLSVANSSSYSHI
    

Molecular Weight11515.29 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)6.60

Net Charge (pH 7.4) 6.16

Charge Density (pH 7.0) 0.0648

GRAVY Index-0.40

Hydrophobic Moment 0.55

Boman Index-0.06

Instability Index42.17

Aliphatic Index 71.67

Aromaticity 0.0686

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4739.80

LogP -54.81

H-bond Donors 171.0

H-bond Acceptors 172.0

Rotatable Bonds 387.0

Heavy Atoms 798.0

Ring Count 15.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151481 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca fascicularis [Animal]

FamilyDefensin

Tax ID9541

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence