Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length246 amino acids

Chemical FormulaC1243H1926N286O370S12

DescriptionStandard

        LSKHKIISVVFVIFCVLSTTLTAVMQIDDLAEVDYSLSGLPAVFQPFIDLDLKGIVFPAGIYTDSPYVAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNMTIAEETCSYFNMNTEIFSSIIPEVAKYSVTPYPVMLKLMSSEIPVIRLQQDSFTVGIQGSMEVLAILPDSTTRSLFTLNIAANTSISLNIFDQKLMGSLCLNRMQFSLAHSNVGSFEVLLLENILSYILQTEVIPSANGK
    

Molecular Weight27181.06 Da

Isoelectric Point (pI)4.34

Net Charge (pH 7.0)-12.07

Net Charge (pH 7.4) -12.47

Charge Density (pH 7.0) -0.0491

GRAVY Index0.47

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index41.42

Aliphatic Index 105.41

Aromaticity 0.1179

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0263126 VERIFIED: NO

Provenance & Taxonomy

OrganismPrunella fulvescens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria