Peptide Database

Peptide NameApl_AvBD-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC118H174N36O28S5

DescriptionStandard

        GSCHFGGCPFHLVKVGRCFGFRSCC
    

Molecular Weight2705.19 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)2.88

Net Charge (pH 7.4) 2.51

Charge Density (pH 7.0) 0.1154

GRAVY Index0.46

Hydrophobic Moment 0.47

Boman Index0.17

Instability Index74.55

Aliphatic Index 38.80

Aromaticity 0.1600

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1000.57

LogP -10.75

H-bond Donors 41.0

H-bond Acceptors 38.0

Rotatable Bonds 83.0

Heavy Atoms 187.0

Ring Count 7.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126297 VERIFIED: YES

Provenance & Taxonomy

OrganismPasser domesticus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)