Peptide Database

Peptide NameFROPDOTA

Function Ontology

Delivery / Targeting ▸ Tumor targeting ▸ Tumor-targeting peptide

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC74H114N14O24S

DescriptionStandard

        EDYELMDLLAYLK
    

Molecular Weight1615.84 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.16

Net Charge (pH 7.4) -3.34

Charge Density (pH 7.0) -0.2432

GRAVY Index-0.12

Hydrophobic Moment 0.29

Boman Index0.10

Instability Index11.72

Aliphatic Index 127.69

Aromaticity 0.1538

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 628.20

LogP -1.12

H-bond Donors 21.0

H-bond Acceptors 22.0

Rotatable Bonds 54.0

Heavy Atoms 113.0

Ring Count 2.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140259 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilySomatostatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermNone

C-Termlys coupled to the chelator DOTA (DOTA is 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid)

Other Mods111In radiolabeling

Bio-Activity Profile

Function

Tumor-Targeting Peptide

Activity0.494 μM

MethodRadioimmunoassay and RP-HPLC

Half-LifeHuman serum, in vitro; 4260 s