Peptide Database

Peptide NameC34S[138T]

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC185H282N50O64S

DescriptionStandard

        WMEWDREINNYTSLIHSLIEETQNQQEKNEQELL
    

Molecular Weight4262.58 Da

Isoelectric Point (pI)4.21

Net Charge (pH 7.0)-6.13

Net Charge (pH 7.4) -6.40

Charge Density (pH 7.0) -0.1804

GRAVY Index-1.27

Hydrophobic Moment 0.58

Boman Index-0.19

Instability Index57.56

Aliphatic Index 80.29

Aromaticity 0.0882

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1916.07

LogP -17.93

H-bond Donors 63.0

H-bond Acceptors 60.0

Rotatable Bonds 147.0

Heavy Atoms 300.0

Ring Count 6.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0397179 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

Tax ID11676

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetHeLa

Activity0.0026±0.0002 μM

MethodIC50

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