Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2300H3652N620O638S11

DescriptionStandard

        TNPGFVVRITQSGLDYAHQQGIAILEKELAQLKLPDISGDTRVLRVGKVHYALSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLVVRDHGSFNLRVENIYIKIILQLGSDTTGKPTISTSGCSARISKVRVLFSGKFGWLYNLFHNVIESRIQKILEDKICDNVVKSVQNDLQTYIRTLPVTAKIGNKTGIDYSLVAPPRATARSLDAELKGEFYSLAHRSTVPFSPLPLAFPSDHKRMVYFGASSYFFNTACIAYHKAGALVFEITEAMIPKDAGFSLDTSVFSAFIPQLEEMYPKMPMKFRLSAPTAPFLTIGPGGISFQPVVDAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGHIVGSLDVGRIRLSLKDSAVGTFQVRTMQSLMNILASSTLLPRLNARLDEGFPLPLLDRIQLSNILVKFHQNFLMLGADVHFQPR
    

Molecular Weight50550.09 Da

Isoelectric Point (pI)9.65

Net Charge (pH 7.0)14.35

Net Charge (pH 7.4) 13.48

Charge Density (pH 7.0) 0.0315

GRAVY Index0.12

Hydrophobic Moment 0.68

Boman Index0.11

Instability Index41.94

Aliphatic Index 104.76

Aromaticity 0.0921

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240181 VERIFIED: NO

Provenance & Taxonomy

OrganismCerthia brachydactyla [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria