Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC427H660N116O116S8

DescriptionStandard

        FKNLPSNMALSRGTFYFGLALFFIVVELPSGSWAGLEYSQSFPGGEFAVCETCRLGRGKCRRTCLDSEKIAGKCKLNFFCCRERI
    

Molecular Weight9531.04 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)4.70

Net Charge (pH 7.4) 4.38

Charge Density (pH 7.0) 0.0553

GRAVY Index0.06

Hydrophobic Moment 0.56

Boman Index0.05

Instability Index38.46

Aliphatic Index 71.18

Aromaticity 0.1412

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3736.76

LogP -34.86

H-bond Donors 140.0

H-bond Acceptors 129.0

Rotatable Bonds 314.0

Heavy Atoms 667.0

Ring Count 16.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0195231 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence