Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC334H512N80O87S7

DescriptionStandard

        MEPQSIFILLVLVVLALHFKENEAASFPWSCASLSGVCRQGVCLPSELYFGPLGCGKGFLCCVSHFL
    

Molecular Weight7264.58 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-1.38

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0205

GRAVY Index0.85

Hydrophobic Moment 0.44

Boman Index0.36

Instability Index37.72

Aliphatic Index 107.61

Aromaticity 0.1194

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2576.16

LogP -17.45

H-bond Donors 93.0

H-bond Acceptors 95.0

Rotatable Bonds 229.0

Heavy Atoms 508.0

Ring Count 15.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0300693 VERIFIED: YES

Provenance & Taxonomy

OrganismDanio rerio [Animal]

FamilyBeta-defensin; Defensin

Tax ID7955

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic