Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC100H152N26O36S4

DescriptionStandard

        GIVEQCCENPCSLYQLENYCN
    

Molecular Weight2422.69 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.27

Net Charge (pH 7.4) -3.54

Charge Density (pH 7.0) -0.1559

GRAVY Index-0.34

Hydrophobic Moment 0.36

Boman Index0.02

Instability Index2.06

Aliphatic Index 69.52

Aromaticity 0.0952

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1024.57

LogP -11.61

H-bond Donors 36.0

H-bond Acceptors 37.0

Rotatable Bonds 77.0

Heavy Atoms 166.0

Ring Count 3.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0257448 VERIFIED: YES

Provenance & Taxonomy

OrganismCairina moschata [Animal]

FamilyInsulin

Tax ID8855

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0417614 VERIFIED: YES

Provenance & Taxonomy

OrganismAnas platyrhynchos [Animal]

FamilyInsulin

Tax ID8839

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

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