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MYP_087872
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Basic Information
Vitri B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C121H186N32O40S6
Standard
Sequence
GYPICGESCVGGICNIPGCSCSWPVCTTN
Physicochemical Analysis
2921.35 Da
4.05
-1.30
-1.59
-0.0447
0.47
0.36
0.31
60.17
60.34
0.0690
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1112.40
-15.30
43.0
45.0
84.0
199.0
6.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016067 VERIFIED: YES
Provenance & Taxonomy
Viola tricolor [Plant]
Cyclotide
214053
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Anticancer Cytotoxic
Human hepatocarcinoma BEL-7402
10 μg/mL
IC50
PaperIsolation and characterization of cytotoxic cyclotides from Viola tricolor PMID20580652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20580652/
RECORD: Rec_0053104 VERIFIED: YES
Provenance & Taxonomy
Plantae [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID20580652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20580652/
RECORD: Rec_0113997 VERIFIED: YES
Provenance & Taxonomy
Plantae [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID20580652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20580652/
RECORD: Rec_0240751 VERIFIED: YES
Provenance & Taxonomy
Viola tricolor [Plant]
Cyclotide
214053
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Anticancer Cytotoxic
Human glioblastoma U251-MG
45.21 μg/mL
IC50
PaperIsolation and characterization of cytotoxic cyclotides from Viola tricolor PMID20580652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20580652/
RECORD: Rec_0276214 VERIFIED: YES
Provenance & Taxonomy
Plantae [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID20580652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20580652/
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