Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length598 amino acids

Chemical FormulaC2807H4501N809O884S9

DescriptionStandard

        MSSGEGKDDHGATRGKKDEPARSGSKRSGVDASDNSGWSSENNPWGGSGDSGIHWGGGSGNGGSDGGGSSGGVNLSLFPEAQASVDLGAPSTLSLVDGLWGFSLVRSSTVQSAIAKALARIKPMAAPAASMLWRGSLWGLVIEAITPTKIAPDDMSKVRHVVLTLPAKEVTKTPLSQLPSQSYALVDVRITDVVESGVQKLALTRAPAYPVSVPVIQARPTKRPGVYAASVVDGMPDIHINVGTQSPVGPQKPSEEVKDVNNAPIVQQPMFTTAAYTEDAIVVFPSGSNASPVYISATPVLTKKQIAELQAEFKRRVAQWDAGHPVEVAERRAFEAGEALKLAQKNVNQKQATLNALKASPEGLALADASKHPISLKEAKFAAIPGYSGGGVHFETTATIENRQQLDQLMTLGALKYLNNVLQWGEVTAPTQDGVKVGNAIKAGTVETYNKLRQQLIDRQKEMNRAQVAFNTAVESRKQAEQGKKKAEDNRDKVKQNNKKPRTDFTTDDKIKEQMIDRGWTEKDIKDVVAKGPKGISVDKRGPSKTPPDFLGRNDDATVYGEPGKYVVINDRTREVAQVSDKTDPDWVDDGRIFWGGK
    

Molecular Weight64014.24 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)6.18

Net Charge (pH 7.4) 5.45

Charge Density (pH 7.0) 0.0103

GRAVY Index-0.51

Hydrophobic Moment 0.63

Boman Index-0.05

Instability Index39.19

Aliphatic Index 75.69

Aromaticity 0.0552

Extinction Coeff. Reduced 75400.00

Extinction Coeff. Oxidized 75400.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025798 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterobacteriaceae bacterium RIT693 [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative

TargetEscherichia coli