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MYP_087847
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Basic Information
Ghrelins
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
28 amino acids
C139H231N45O41
Standard
Sequence
GSSFLSPEHQKAQQRKESKKPPAKLQPR
Physicochemical Analysis
3188.60 Da
10.56
4.85
4.58
0.1731
-1.74
0.39
-0.47
73.35
35.00
0.0357
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1424.32
-17.58
47.0
47.0
109.0
225.0
6.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032838 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Motilin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Gastrointestinal
PMID10604470 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10604470/
RECORD: Rec_0053254 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]; Rattus norvegicus [Animal]
10090; 10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0071028 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0188242 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Ghrelin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Fatty acid ie n-octanoic acid present at serine at position 3, (125)I labelling
Bio-Activity Profile
Growth hormone secretagogue Appetite stimulation
Radioactivity measured by scintillation counter
Administered into blood of rats, in vivo; 990 s
PMID22592200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22592200/
RECORD: Rec_0196819 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Ghrelins
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation Sleep regulation Wake regulation Feeding regulator
Experimental: 15-18 minutes; /990 seconds; Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Ghrelins (Rattus norvegicus): PMID 22592200 PMID22592200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22592200/
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