Peptide Database

Peptide NameUnnamed

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC40H47N7O11

DescriptionStandard

        YPFGFDG
    

Molecular Weight801.84 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.1771

GRAVY Index-0.23

Hydrophobic Moment 0.17

Boman Index0.40

Instability Index71.34

Aliphatic Index 0.00

Aromaticity 0.4286

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 286.66

LogP -1.02

H-bond Donors 9.0

H-bond Acceptors 10.0

Rotatable Bonds 20.0

Heavy Atoms 58.0

Ring Count 4.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0117847 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid

Targetmu opioid receptor

Activity0.07 μM

MethodIC50

PaperDooley C.T., Kaplan R.A., Chung N.N., Schiller P.W., Bidlack J.M., Houghten R.A.. Six highly active mu-selective opioid peptides identified from two synthetic combinatorial libraries. Peptide Research, 8, 3, 124-137(1995). PMID7670227 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7670227/

RECORD: Rec_0144398 VERIFIED: NO