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MYP_087791
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Basic Information
Beta-defensin 14 (BD-14, mBD-14; Defensin, beta 14; Rodents, mammals, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Standard
45 amino acids
C221H380N76O56S6
Standard
Sequence
FLPKTLRKFFCRIRGGRCAVLNCLGKEEQIGRCSNSGRKCCRKKK
Physicochemical Analysis
5190.25 Da
10.41
11.70
11.39
0.2600
-0.64
0.76
-0.36
32.47
60.67
0.0667
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2214.93
-24.49
87.0
74.0
185.0
359.0
4.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0193435 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID14718547 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14718547/
RECORD: Rec_0217037 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 28.9%, T 37.8%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative Chemotactic
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0304127 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
yeast Candida albicans ATCC 24433
1.2 μM
MBC
PaperIdentification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3.
RECORD: Rec_0335226 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]; Mammalia [Animal]
Defensin
10090; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-33; 18-40; 23-41
Bio-Activity Profile
Antimicrobial
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