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MYP_087791
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Basic Information
Beta-defensin 14 (BD-14, mBD-14; Defensin, beta 14; Rodents, mammals, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Standard
45 amino acids
C221H380N76O56S6
Standard
Sequence
FLPKTLRKFFCRIRGGRCAVLNCLGKEEQIGRCSNSGRKCCRKKK
Physicochemical Analysis
5190.25 Da
10.41
11.70
11.39
0.2600
-0.64
0.76
-0.36
32.47
60.67
0.0667
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2214.93
-24.49
87.0
74.0
185.0
359.0
4.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003284 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPubMed PMID: 15489334 | PubMed PMID: 18167348 PMID15489334;18167348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15489334/
RECORD: Rec_0020996 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Chemotactic
Escherichia coli
RECORD: Rec_0106741 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
S. enterica serovar Typhimurium ATCC 13311
0.6-1.2 μM
MBC
PaperIdentification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3.
RECORD: Rec_0158443 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0170179 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
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