Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC495H832N132O132S9

DescriptionStandard

        MKNLLLVLTITLLLAQVTSGMKCWKRLGNCRTMCQKNEVFHILCNNLAKCCVKPKNIPVKFTSSNTSIQSTRSVVLLSNYILRSSISFYIVPIILISL
    

Molecular Weight11033.29 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.15

Charge Density (pH 7.0) 0.1074

GRAVY Index0.52

Hydrophobic Moment 0.68

Boman Index0.15

Instability Index49.39

Aliphatic Index 125.20

Aromaticity 0.0612

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4275.77

LogP -37.87

H-bond Donors 156.0

H-bond Acceptors 153.0

Rotatable Bonds 373.0

Heavy Atoms 768.0

Ring Count 11.0

Amide Bonds 108.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383313 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic