‹ ›
MYP_087782
← PREVIOUS NEXT → BACK
Basic Information
Hp1404-T1b
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C63H117N15O16
Standard
Sequence
ILKKLLEGVKSI
Physicochemical Analysis
1340.69 Da
9.70
1.76
1.55
0.1467
0.68
0.70
0.17
8.67
186.67
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
519.01
-1.51
18.0
18.0
50.0
94.0
0.0
11.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0038375 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
25 μM
MIC
PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0040685 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-negative
Pseudomonas aeruginosa 4319
25 μM
MIC
PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0055355 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
PaperMechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa. Sci Rep. 2018 Jan 29;8(1):1763. doi: 10.1038/s41598-018-19434-7. PMID: 29379033. PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0067768 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent KR 20190033837 A Evidence URLhttps://patents.google.com/patent/KR20190033837A/en PatentKR 20190033837 A
RECORD: Rec_0089669 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-negative
Pseudomonas aeruginosa 559
25 μM
MIC
PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
1 2 3 ... 5 NEXT LAST
Showing 5 records on this page · Page 1 of 5