Peptide Database

Peptide NameProtegrin 3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length149 amino acids

Chemical FormulaC719H1171N211O217S10

DescriptionStandard

        METQRASLCLGRWSLWLLLLGLVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRQPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEVQGVRGGGLCYCRRRFCVCVGRG
    

Molecular Weight16563.92 Da

Isoelectric Point (pI)8.08

Net Charge (pH 7.0)1.44

Net Charge (pH 7.4) 1.06

Charge Density (pH 7.0) 0.0097

GRAVY Index-0.29

Hydrophobic Moment 0.77

Boman Index-0.08

Instability Index37.85

Aliphatic Index 87.58

Aromaticity 0.0537

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6900.58

LogP -72.37

H-bond Donors 247.0

H-bond Acceptors 229.0

Rotatable Bonds 544.0

Heavy Atoms 1157.0

Ring Count 21.0

Amide Bonds 160.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0003917 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin family

Tax ID9823

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic

MethodQualitative functional evidence