Peptide Database

Peptide NameHBD-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC217H339N65O64S6

DescriptionStandard

        GNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK
    

Molecular Weight5074.80 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)4.87

Net Charge (pH 7.4) 4.47

Charge Density (pH 7.0) 0.1036

GRAVY Index-0.28

Hydrophobic Moment 0.49

Boman Index-0.01

Instability Index31.30

Aliphatic Index 51.91

Aromaticity 0.1064

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2090.33

LogP -26.70

H-bond Donors 80.0

H-bond Acceptors 77.0

Rotatable Bonds 166.0

Heavy Atoms 352.0

Ring Count 8.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058711 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus

RECORD: Rec_0119851 VERIFIED: YES