Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC438H712N128O125S9

DescriptionStandard

        MLLTRSSTLSGHIKLWFLTLAVLVVLAQTSPEGWFRTCFYGMGKCRHVCRANEKKKERCGENSFCCLGETKSKLSNIPTNKGRKKDESC
    

Molecular Weight10059.71 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)8.61

Net Charge (pH 7.4) 8.17

Charge Density (pH 7.0) 0.0968

GRAVY Index-0.37

Hydrophobic Moment 0.56

Boman Index-0.10

Instability Index44.85

Aliphatic Index 68.99

Aromaticity 0.0787

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4127.31

LogP -44.05

H-bond Donors 155.0

H-bond Acceptors 145.0

Rotatable Bonds 344.0

Heavy Atoms 700.0

Ring Count 13.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0193009 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence