‹ ›
MYP_087667
← PREVIOUS NEXT → BACK
Basic Information
Phylloseptin-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C93H160N22O23
Standard
Sequence
FLSLIPKIAGGIASLVKNL
Physicochemical Analysis
1954.40 Da
10.00
1.76
1.55
0.0925
1.26
0.54
0.46
4.00
169.47
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
713.92
-3.73
24.0
25.0
65.0
138.0
2.0
19.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0237626 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa trinitatis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Anticancer Anti-inflammatory Cytotoxic Hemolytic
Staphylococcus epidermidis
PMID29980138;30734396 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29980138/
RECORD: Rec_0295612 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa trinitatis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
50 μM
MIC
PMID29980138 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29980138/
RECORD: Rec_0297388 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa trinitatis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus epidermidis
6.25 μM
MIC
PaperPeptidomic analysis of the host-defense peptides in skin secretions of the Trinidadian leaf frog Phyllomedusa trinitatis (Phyllomedusidae).
RECORD: Rec_0311317 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Phylloseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ4436
RECORD: Rec_0362772 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa trinitatis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
25 μM
MIC
PMID29980138 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29980138/
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records on this page · Page 2 of 3