Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length509 amino acids

Chemical FormulaC2568H3997N655O735S15

DescriptionStandard

        MRTKQVPVLGACFLLWSLYIASSQTVYPGIKARITQRALDYGLQVGMEILEQLAKEIVIPDLNGSESLKFLKIDYVKYNFSNIKINAFSFPNTSLAFVPGVGIRALSNHGTANISTNWDVKAPLFQDSGAADLFLSGIYFTGIIVFTRNDFGHPALELQDCHVQVSHARVSFSGGLSVLYNSFAEPMEKPILKNLNEMVQLCPIAISQVEEFNVNISALEVLTKIDNYTVLDCSLISPPEVTENHLDFHLKGAFYPLESLVDPPFTPAPFELPESRDSMLYIGVSEYFFKSASFAHFVSGALGTVLSTREISNYFNQNAQGIGSVLSKIAEIYILSQPFMLQIMATGPPVVNLHPNNFSLELPAAVIMLTQPENSTIQPIVSMDFVASTSVGLAILGQKLICSLSLNRFRLSLPENSPRDIKVVRFENILSSILHFGVLPLANTKLQQGFPLPNPYNISFINSDIEVLEGFLLISTDVAHETSSKQQPNLHSWGHLNMVHGPRRKQPIH
    

Molecular Weight56287.13 Da

Isoelectric Point (pI)5.78

Net Charge (pH 7.0)-9.27

Net Charge (pH 7.4) -10.37

Charge Density (pH 7.0) -0.0182

GRAVY Index0.15

Hydrophobic Moment 0.68

Boman Index0.18

Instability Index37.50

Aliphatic Index 103.79

Aromaticity 0.0963

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37610.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0308477 VERIFIED: NO

Provenance & Taxonomy

OrganismRanitomeya imitator [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria