Peptide Database

Peptide NameHuman granulysin

Function Ontology

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Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC129H219N39O36S2

DescriptionStandard

        GRDYRTCLTIVQKLKKMVDKPTQHP
    

Molecular Weight2956.49 Da

Isoelectric Point (pI)9.86

Net Charge (pH 7.0)3.83

Net Charge (pH 7.4) 3.56

Charge Density (pH 7.0) 0.1534

GRAVY Index-0.96

Hydrophobic Moment 0.73

Boman Index-0.30

Instability Index-3.20

Aliphatic Index 70.00

Aromaticity 0.0400

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1242.40

LogP -11.61

H-bond Donors 44.0

H-bond Acceptors 43.0

Rotatable Bonds 100.0

Heavy Atoms 206.0

Ring Count 4.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063255 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)