Peptide Database

Peptide NameColicin-M

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length464 amino acids

Chemical FormulaC2291H3582N614O676S12

DescriptionStandard

        MVDETNYNNGVPPQTGLVWSGVSWGWPTNGSWGNDTLTVWPKNNNGSIQNYIELITESGKFDPLTGNGWKPSVDGMWEFSPQKARKETINAVNKIKNGVNAGQPDILLSVDFWSFKVAPSEVTEFTSINPVVTILPAELMTGTKMNINSAAPKSIKVHSRILDDVHDGKQFLSVVGAKGNSYNLPVIQAKQRGKNFYVGRMPGLLGFLEFYINNGSVTEQQQYYLASSENGQLRQSGATVGERTDDIIVWFPKGSNRTPVYVSFTRVLTADGLAKRNDAEKKANDEIQKAIKATADFYKELAKRFGEQQSKIALELADGAKGKRIRSADEAMAAFNKYKASMDKKFSVKDRQAIGKALESIDRNLMASSLAKFSKGLAGVSYFIDEMGLVNAFINSNKTGDWRQFFVKAEVLGAGMAASAFVAFTFAALTASPLGILGFSLIMFLTGALIDDKLMRTLHDKLFL
    

Molecular Weight50927.44 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)7.80

Net Charge (pH 7.4) 7.31

Charge Density (pH 7.0) 0.0168

GRAVY Index-0.24

Hydrophobic Moment 0.74

Boman Index0.05

Instability Index27.84

Aliphatic Index 81.59

Aromaticity 0.1013

Extinction Coeff. Reduced 71390.00

Extinction Coeff. Oxidized 71390.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307643 VERIFIED: NO

Provenance & Taxonomy

OrganismCitrobacter amalonaticus [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence