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MYP_087525
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Basic Information
VpAmp2.0
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
25 amino acids
C122H195N31O31S
Standard
Sequence
FWGFLGKLAMKAVPSLIGGNKSSSK
Physicochemical Analysis
2624.11 Da
10.48
3.76
3.55
0.1502
0.19
0.51
0.21
40.49
82.00
0.1200
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
996.81
-8.73
35.0
36.0
88.0
185.0
5.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0201912 VERIFIED: YES
Provenance & Taxonomy
Vaejovis punctatus [Animal]
VpAm
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperPeptides. 2015 Sep 4;73:51-59 | https://www.ncbi.nlm.nih.gov/pubmed/26352292 PMID26352292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26352292/
RECORD: Rec_0206416 VERIFIED: YES
Provenance & Taxonomy
Mesomexovis punctatus [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0219295 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Mycobacterium tuberculosis
30.5
MIC
PMID26352292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26352292/
RECORD: Rec_0230996 VERIFIED: YES
Provenance & Taxonomy
Vaejovis punctatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
12.5 μM
MIC
RECORD: Rec_0235025 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis H37Rv
7.5 μM
MIC
PMID26352292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26352292/
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