Peptide Database

Peptide NameSpiderine OtTx1a

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Insecticidal/Pest control ▸ Insecticidal activity

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC531H837N151O149S10

DescriptionStandard

        KFKWGKLFSTAKKLYKKGKKLSKNKNFKKALKFGKQLAKNLQAGEEHEPGTPVGNNKCWAIGTTCSDDCDCCPEHHCHCPAGKWLPGLFRCTCQVTESDKVNKCPPAE
    

Molecular Weight12040.90 Da

Isoelectric Point (pI)9.29

Net Charge (pH 7.0)11.02

Net Charge (pH 7.4) 10.42

Charge Density (pH 7.0) 0.1020

GRAVY Index-0.82

Hydrophobic Moment 0.72

Boman Index-0.15

Instability Index34.50

Aliphatic Index 47.04

Aromaticity 0.0833

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4843.22

LogP -50.25

H-bond Donors 172.0

H-bond Acceptors 174.0

Rotatable Bonds 406.0

Heavy Atoms 841.0

Ring Count 23.0

Amide Bonds 116.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0411052 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct based on Oxyopes takobius [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Insecticidal

TargetEnterococcus faecalis VKM B-871

Activity5-10 μM

MethodMIC

FIRST PREV 1 2 3

Showing 1 records on this page Ã‚Â· Page 3 of 3