Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC858H1357N237O229S7

DescriptionStandard

        HEPMLLLAITEFVANSAAFTYFTAGALERNISSDMLPRRFPLQLKTKSMGLFSPQLHERYPNHPMELHLSARRQPQLSCRPDALHGALFSSAEAFVVLPNATRVPAFLLNIDANVTGKPIITRNRLGGTVSLKGVLSVLQVKRLENLLKFALWLFGVPWANSECCPHPVP
    

Molecular Weight18880.86 Da

Isoelectric Point (pI)9.66

Net Charge (pH 7.0)6.27

Net Charge (pH 7.4) 5.69

Charge Density (pH 7.0) 0.0369

GRAVY Index0.08

Hydrophobic Moment 0.62

Boman Index0.10

Instability Index50.97

Aliphatic Index 99.29

Aromaticity 0.0824

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7348.67

LogP -72.38

H-bond Donors 253.0

H-bond Acceptors 248.0

Rotatable Bonds 603.0

Heavy Atoms 1331.0

Ring Count 37.0

Amide Bonds 183.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038709 VERIFIED: NO

Provenance & Taxonomy

OrganismRynchops niger [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria