Peptide Database

Peptide NameBovine Beta-defensin 8

Function Ontology

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Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC181H306N68O45S6

DescriptionStandard

        ARNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCR
    

Molecular Weight4347.18 Da

Isoelectric Point (pI)11.20

Net Charge (pH 7.0)8.82

Net Charge (pH 7.4) 8.49

Charge Density (pH 7.0) 0.2322

GRAVY Index-0.35

Hydrophobic Moment 0.76

Boman Index-0.26

Instability Index15.28

Aliphatic Index 58.95

Aromaticity 0.0526

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1853.51

LogP -22.68

H-bond Donors 74.0

H-bond Acceptors 61.0

Rotatable Bonds 140.0

Heavy Atoms 300.0

Ring Count 6.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0121150 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)