Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC380H605N99O107S11

DescriptionStandard

        MKISFSSVLFLLMIVFIISSSGNKKMVGEAKDCFQTWTCEGGRKCREKCTAKYKGIGRCDEITAPIVPPQCNCYYPC
    

Molecular Weight8625.18 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)4.42

Net Charge (pH 7.4) 4.07

Charge Density (pH 7.0) 0.0574

GRAVY Index0.01

Hydrophobic Moment 0.49

Boman Index0.05

Instability Index33.80

Aliphatic Index 69.61

Aromaticity 0.1039

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3308.56

LogP -30.57

H-bond Donors 123.0

H-bond Acceptors 123.0

Rotatable Bonds 286.0

Heavy Atoms 597.0

Ring Count 13.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0054216 VERIFIED: NO

Provenance & Taxonomy

OrganismBrassica oleracea var. oleracea [Plant]

FamilyDefensin

Tax ID3712

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence