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MYP_087479
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Basic Information
Bacteriocin ASP-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
7 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FTVAXFI
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0132969 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
1423
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
None
X=dehydrobutyrine
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 28887200 PMID28887200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28887200/
RECORD: Rec_0177205 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
1423
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
None
X=dehydrobutyrine
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
280 μg/mL
IC50
PaperPubMed PMID: 28887200 PMID28887200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28887200/
RECORD: Rec_0204876 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
1423
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
None
X=dehydrobutyrine
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
<5 %
Hemolysis
PaperPubMed PMID: 28887200 PMID28887200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28887200/
RECORD: Rec_0290015 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
1423
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
None
X=dehydrobutyrine
Bio-Activity Profile
Antimicrobial Anticancer
HepG2
192 μg/mL
IC50
PaperPubMed PMID: 28887200 PMID28887200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28887200/
RECORD: Rec_0421517 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
1423
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
None
X=dehydrobutyrine
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 28887200 PMID28887200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28887200/