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MYP_087458
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Basic Information
GRGDf-Mitoparan, GRGDf-Mastoparan [A5,8K; A10Aib]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GRGDFINLKKLAKLXKKIL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0038615 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 15
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
6.67
MIC
PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0059175 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 15
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa
32 μg/mL
MIC
PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0171832 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 15
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
13.33
MIC
PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0172602 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 15
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa
32 μg/mL
PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0197867 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 15
Bio-Activity Profile
Cytotoxic
Human embryonic kidney HEK293 cells
16.7-19.7 μg/mL
Cytotoxicity
PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
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