Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC557H888N148O166S3

DescriptionStandard

        PDLTGYEKFGLGNVKYNISRIHVTAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFRDSGRSTVYISKVFVTAIFSTPLDNAGHTLISLTSCRTTSGDIEIKLNGKS
    

Molecular Weight12410.10 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)3.13

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.10

Hydrophobic Moment 0.55

Boman Index0.14

Instability Index23.01

Aliphatic Index 97.46

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5032.29

LogP -53.33

H-bond Donors 181.0

H-bond Acceptors 174.0

Rotatable Bonds 408.0

Heavy Atoms 874.0

Ring Count 18.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040773 VERIFIED: NO

Provenance & Taxonomy

OrganismAnhinga rufa [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria