Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC430H671N121O121S13

DescriptionStandard

        MKAFSIAVAVMLVLACMFILESTAVPFSEVRTEEVGSIDSPVGEHQQPGSESMRLPEHFRFKRQSHLSLCRWCCNCCHNKGCGFCCKF
    

Molecular Weight9888.51 Da

Isoelectric Point (pI)7.56

Net Charge (pH 7.0)0.78

Net Charge (pH 7.4) 0.21

Charge Density (pH 7.0) 0.0088

GRAVY Index0.11

Hydrophobic Moment 0.49

Boman Index0.07

Instability Index74.66

Aliphatic Index 68.64

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3840.33

LogP -37.87

H-bond Donors 142.0

H-bond Acceptors 139.0

Rotatable Bonds 324.0

Heavy Atoms 685.0

Ring Count 17.0

Amide Bonds 92.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0223618 VERIFIED: NO

Provenance & Taxonomy

OrganismHucho hucho [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal