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MYP_087340
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Basic Information
Frenatin 4.1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C116H185N29O34
Standard
Sequence
GFLEKLKTGAKDFASAFVNSIKGT
Physicochemical Analysis
2529.88 Da
9.53
1.76
1.55
0.0733
-0.01
0.57
0.11
-18.32
73.33
0.1250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1035.31
-10.50
36.0
36.0
87.0
179.0
3.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0026199 VERIFIED: YES
Provenance & Taxonomy
Litoria infrafrenata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
512 μg/mL
MIC
PMID27792198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27792198/
RECORD: Rec_0146609 VERIFIED: YES
Provenance & Taxonomy
Litoria infrafrenata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
512 μg/mL
MIC
PMID27792198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27792198/
RECORD: Rec_0194867 VERIFIED: YES
Provenance & Taxonomy
Litoria infrafrenata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes (<5% Hemolysis at 512 microg/ml
512 μg/mL
Hemolysis
PMID27792198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27792198/
RECORD: Rec_0197538 VERIFIED: YES
Provenance & Taxonomy
Litoria infrafrenata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli
512 μg/mL
MIC
PMID27792198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27792198/
RECORD: Rec_0351515 VERIFIED: YES
Provenance & Taxonomy
Litoria infrafrenata [Animal]
Frenatin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperM.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
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